Importantly, MCMV-infected eyes of MAIDS-10 mice deficient in either caspase-1, GSDMD, or IL-18 all consistently showed a pattern of retinal disease similar, if not identical, to that observed in the present study for MAIDS-10 mice deficient in the NLRP3, NLRP1b, or AIM2 inflammasomes. This evidence concerns the gene AIM2 and Abnormal retinal morphology.