NLRP3 and Abnormal retinal morphology: Because 100% of MCMV-infected eyes of all MAIDS-10 mice deficient in either NLRP3, NLRP1b, or AIM2 inflammasome production failed to show typical full-thickness retinal necrosis at 10 days postinfection, this prompted us to perform a more rigorous histopathologic analysis of all animal groups to define and compare their patterns of retinal disease in more detail.