According to meta-analysis data, certain polyphenolic compounds (curcumin, resveratrol, naringenin, anthocyanin, hesperidin, catechin, silymarin, and genistein) exhibit therapeutic effects in NAFLD, contributing to reductions in body mass index, aspartate aminotransferase and alanine aminotransferase levels, triglyceride and total cholesterol concentrations, as well as improvements in insulin resistance and hepatic fat infiltration in patients with this disorder [23]. This evidence concerns the gene GPT and Insulin resistance.