In addition, Grabar et al. stratified patients according to their CD4+ T lymphocyte count into ≤50, 51–100 and 101–200 cells/mm3 groups and reported that, overall, the highest risk for KS was in patients with less than 50 cells/mm3, who had a 5-fold greater risk, and these patients had a 12-fold greater risk of visceral KS [29]. This evidence concerns the gene CD4 and Kaposi's sarcoma.