Members of the TLR family that have been shown to be involved in responses to viral infection, in part including that of SARS-CoV-2, are TLR1, TLR2, TLR3, TLR4, TLR6, TLR7, TLR8 and TLR9 (Figure 1) [31,32]. The gene discussed is TLR7; the disease is viral infectious disease.