In the matched cohorts (GLP-1 RA vs. DPP-4 inhibitors and GLP-1 RA vs. sulfonylureas), the proportion of men was 53.32% and 51.50%, the mean (SD) age was 51.24 (12.67) and 52.66 (13.33) years, the mean (SD) diabetes duration was 7.17 (3.71) and 7.14 (3.76) years, and the mean (SD) follow-up was 3.45 (1.99) and 3.43 (2.00) years, respectively. This evidence concerns the gene GLP1R and diabetes mellitus.