A causative gene for Weill–Marchesani syndrome [28,36,84], which presents with short stature, brachydactyly, microspherophakia, ectopia lentis and myopia, LTBP2 has also been linked with congenital glaucoma associated with isolated microspherophakia [16], ectopia lentis (c.4825T>A p.(Cys1609Ser) and c.529T>C p.(Trp177Arg) variants) [37] and congenital cataracts (c.895C>T p.(Arg299*) variant) [12]. This evidence concerns the gene LTBP2 and congenital glaucoma.