CPAMD8 variants have been linked to anterior segment dysgenesis associated with both congenital and juvenile glaucoma [16,39,40,41], with the variants c.4298C>A p.(Thr1433Asn) and c.2352dupC p.(Arg785Glnfs*23) identified in more than one family [40]. Here, CPAMD8 is linked to Juvenile glaucoma.