However, the QHTTF group showed a certain degree of increase in the expression of PPARα and PPARγ, as well as AMPK and P-AMPK proteins (p < 0.05), suggesting that the traditional Chinese medicine formula may improve glucose and lipid metabolism disorders in ZDF rats by regulating the expression of hepatic PPARα, PPARγ, and AMPK proteins. The gene discussed is PPARA; the disease is Disorder of lipid metabolism.