PPARG and Disorder of lipid metabolism: However, the QHTTF group showed a certain degree of increase in the expression of PPARα and PPARγ, as well as AMPK and P-AMPK proteins (p < 0.05), suggesting that the traditional Chinese medicine formula may improve glucose and lipid metabolism disorders in ZDF rats by regulating the expression of hepatic PPARα, PPARγ, and AMPK proteins.