Dose-dependent enhanced cytotoxicity in triple-negative breast cancer (TNBC) cells. Induced cell cycle arrest at Sub-G1 and G2/M phases.Downregulated anti-apoptotic genes (survivin, cyclin-B1, Bcl-xl).Upregulated pro-apoptotic genes (Bax, Bid).Better apoptotic and antiproliferative properties. This evidence concerns the gene CCNB1 and triple-negative breast carcinoma.