Even though their study evaluated cardiovascular risk based on coronary artery calcification (CAC) instead of direct echocardiographic modifications, both sets of findings underscore IL-6 as a more clinically significant biomarker in renal disease compared to TNF-α.While LVH emerged as a relevant correlate, our analytic strategy was not limited to comparing patients with and without LVH. The gene discussed is IL6; the disease is kidney disorder.