Pulmonary fibrosis pathogenesis involves alveolar epithelial cell injury, activation of pulmonary fibroblasts into matrix-producing myofibroblasts, and a self-perpetuating cycle of epithelial damage and fibroblast activation, primarily driven by TGF-β signaling and interstitial pericytes [15]. This evidence concerns the gene TGFB1 and pulmonary fibrosis.