GH1 and Adrenal insufficiency: In the second case, maximal cortisol concentration during GST was 12.8 μg/dL versus 16.1 μg/dL on ITT (male, after two transsphenoidal surgeries for GH-producing adenoma, about 10 mm in size), while in the last case maximal cortisol concentration was 11.2 μg/dL on GST and 10.2 μg/dL in ITT (female, glucocorticoid-induced adrenal insufficiency).