Angiogenesis, driven by vascular endothelial growth factor (VEGF) and other proangiogenic factors like Fibroblast Growth Factor (FGF), Platelet-Derived Growth Factor (PDGF), and Transforming Growth Factor-Beta (TGF-β), is in particular crucial for tumor progression, especially in metastases to highly vascularized organs such as the liver [8]. The gene discussed is VEGFA; the disease is neoplasm.