Children with Leber congenital amaurosis (LCA) carry a disproportionate risk: a masked school survey found KC in 29% of LCA pupils [3], and 25% of those with biallelic AIPL1 variants develop KC during childhood, likely amplified by the oculo-digital eye-rubbing phenomenon [4]. This evidence concerns the gene AIPL1 and Leber congenital amaurosis.