According to other studies [30,49], our PLWH diagnosed with skin cancers were slightly older than PLWH without skin cancers (mean age difference: 5.7 years), whereas no differences were found regarding sex, photodamage, number of nevi, family history for melanoma, CD4+ T cell count, HIV RNA load and time in antiretroviral therapy. The gene discussed is CD4; the disease is skin neoplasm.