ABCG2 and cancer: The experimental cohort exhibited marked enrichment in 17 key pathways including cofactor biosynthesis, flavonoid pathways (flavone/flavonol, isoflavonoid, degradation), plant secondary metabolism (general, phenylpropanoids, terpenoids/steroids, hormones), lipid metabolism (linoleic acid), transport systems (ABC transporters), cancer metabolism (central carbon), protein digestion/absorption, neuroactive ligand-receptor interactions, bile secretion, and steroid hormone biosynthesis