Another preclinical study using DQ8-Dd-villin-IL-15tg mice with predisposition to CeD reported that cocoa supplementation alongside gliadin managed to prevent the increase in anti-gliadin and anti-TG2 Abs, the latter only in male animals, where a decrease in fecal humidity was also found. This evidence concerns the gene TGM2 and cranioectodermal dysplasia.