In contrast, the genotype IL-10_rs1800872 TT in untreated patients with an OR = 4.36 (CI95% = 1.23–15.54, p = 0.040) was linked to an increased PD risk, but being heterozygous for this variant has a protective effect (OR = 0.20; CI95% = 0.05–0.78, p = 0.030) in controls. This evidence concerns the gene IL10 and Parkinson disease.