Supplementary Figure S1A–F depict the cell type-specific distribution of APP, SNCA, APOE, BDNF, CASS4, and DNMTB3A in donor control, TOF DCM, HCM, HF-HLHS, and Neo-HLHS. Further, violin plots further demonstrate age-dependent expression patterns of key genes (APP, SNCA, and DNMT1) in control donors and CHD subtypes (Figure 3C–E). Here, SNCA is linked to familial dilated cardiomyopathy.