Genes like NRXN3, CADM2, and HCN1 (implicated in synaptic adhesion and ion channel activity) show enriched expression in CHD-associated cardiac neurons (Figure 2A–E), aligning with prior reports linking neural crest cell migration defects to outflow tract malformations [43,44,45]. This evidence concerns the gene NRXN3 and coronary artery disorder.