Univariable analysis revealed that obesity (β = −2.591, p = 0.013), NT-proBNP (β = 2.578, p = 0.015), LV end-diastolic indexed volume (β = 2.551, p = 0.014), LV end-systolic indexed volume (β = 2.984, p = 0.004), RV end-diastolic indexed volume (β = 3.525, p = 0.001), RV end-systolic indexed volume (β = 3.446, p = 0.001), RV stroke volume indexed (β = 3.182, p = 0.002), RV global longitudinal strain (β = 4.414, p = 0.001), and right atrial conduit function (β = 1.992, p = 0.04) were associated with T1 liver mapping. Here, NPPB is linked to obesity due to melanocortin 4 receptor deficiency.