S100A9 and polycystic ovary syndrome: The integration of EV-derived miRNA panels (miR-16-2-3p, miR-378a-3p, miR-483-5p, miR-34a-5p, miR-93-3p, and miR-152-3p) with protein markers (DENND1A.V2 and S100-A9), alongside lipidomic profiling and AI-assisted analysis, may facilitate precision reproductive medicine tailored to the molecular phenotype of each obese PCOS patient.