JCHAIN and neoplasm: Firstly, we revalidated the expression of JCHAIN in breast cancer in the GSE10780, GSE109169, GSE134359, GSE29044, GSE50428, GSE53752, GSE54002, GSE61304, GSE65194, and GSE76250 datasets, and found that the expression of JCHAIN was lower in tumours compared to normal samples (Figure S5A).