The relationship between DFI and JCHAIN expression was later investigated, and it was discovered that high JCHAIN expression in Bladder Urothelial Carcinoma (BLCA), CHOL, COAD, Brain Lower Grade Glioma (LGG), LIHC, and UCEC was associated with good DFI (Figure 4D). This evidence concerns the gene JCHAIN and central nervous system cancer.