HNF1B and Intellectual disability: The effects on neurodevelopment of HNF1B intragenic single nucleotide variants (SNVs) are still a matter of debate, as some authors suggest that HNF1B loss-of-function can contribute to intellectual disability and other disorders, while other studies indicate that the prevalence of NDD in patients with HNF1B SNV does not differ significantly from the prevalence observed in the general population [24,25].