LDHA and Parkinson disease: The bioactivation of benomyl to MBT-SO, a potent ALDH inhibitor, implicates this pesticide as a potential factor in Parkinson’s disease etiology and reinforces the utility of C. elegans as a robust experimental model for toxicity evaluation [85], positioning it in the framework of the New Approach Methodologies (NAMs) with the ability to link molecular events with organism-level outcomes.