GBA1 and Parkinson disease: Additionally, in the current study, we analyzed differentially abundant EV lipids across three pairwise comparisons, GBA1-PD (p.L444P) vs. controls, GBA1-PD (p.N370S) vs. controls, and GBA1-PD (p.N370S) vs. GBA1-PD (p.L444P), using thresholds of log2 fold change > log2(1.5) and p-value < 0.05.