Interestingly, plasma EVs in GBA1-PD (p.N370S) were characterized by a larger size, 126.5 (49.9–491.3) nm, compared to those in GBA1-PD (p.L444P), 112.7 (48.4–445.7) nm, and controls (p < 0.0001 and p < 0.001, respectively) (Figure 3B,C). Here, GBA1 is linked to Parkinson disease.