Several significantly enriched pathways were identified (Figure 3c), with the most prominent being pathways in cancer, proteoglycans in cancer, relaxin signaling, fluid shear stress and atherosclerosis, estrogen signaling, endocrine resistance, AGE–RAGE signaling in diabetic complications, parathyroid hormone signaling, and HIF-1 signaling. This evidence concerns the gene HIF1A and atherosclerosis.