Glutathione S-transferase (GST) activity was significantly elevated in the SCY group (34.25 ± 1.51 nmol/min/mg), the SCF group (32.40 ± 4.40 nmol/min/mg), and the SCA group (18.32 ± 1.28 nmol/min/mg), compared to the control group (8.91 ± 0.24 nmol/min/mg). This evidence concerns the gene KITLG and autosomal dominant cerebellar ataxia.