Interestingly, eight pathways were shared among TNBC tumors with obesity of both racial groups due to the interactions of different miRNAs of the sets AA and EA with the same related mRNA targets, i.e., ESR1 and ES32 DE in EA and ERBB4 DE in AA, and these belong to the same pathway, ‘Constitutive Signaling by Aberrant PI3K in Cancer’. Here, ESR1 is linked to obesity due to melanocortin 4 receptor deficiency.