Thirteen (13) genes were further prioritized across all comparisons, mapped in previous risk loci for AD including MRPS21 and TNFSF4 in chromosome 1, KIAA1109, ADAD1, IL1 and IL21 in chromosome 4, BACH2 in chromosome 6, IL2RA in chromosome 10, CLEC16A in chromosome 16, ZBTB46, ARFRP1 and TNFRSF6B in chromosome 20 and CSF2RB in chromosome 22 (Figure S4). The gene discussed is CLEC16A; the disease is Alzheimer disease.