Contrastingly, genetically predicted overexpression of SUOX in whole blood (β, 95% CI: −0.158, −0.219–−0.096), p-value = 5 × 10−7) and small intestine (β, 95% CI: −0.085, −0.12–−0.05, p-value = 1.33 × 10−6) as well as TNFRSF11A in sun-exposed skin (β, 95% CI: −0.078, −0.123–−0.034, p-value = 5.6 × 10−4) reported protective effects in AD risk (Table S6). This evidence concerns the gene TNFRSF11A and Alzheimer disease.