IDH2 and glioblastoma: According to the 2021 WHO classification, tumors formerly known as adult-type diffuse gliomas are now categorized into three types: astrocytoma, isocitrate dehydrogenase (IDH) mutant; oligodendroglioma, IDH mutant and 1p/19q codeleted; and glioblastoma, IDH wild-type [2].