A tumor cells cluster was identified by including cells with high expression of the following genes: Mki67, Pcna (proliferating cell nuclear antigen), and Top2a (DNA topoisomerase II alpha) (proliferation markers); Sox2 (SRY-box transcription factor 2) and Nes (Nestin) (stem cell markers); oligodendrocyte transcription factor 2 Olig2; and Pdgfra (platelet-derived growth factor receptor A) as a vascularization marker. This evidence concerns the gene TOP2A and neoplasm.