PFKFB3 and breast cancer: Regarding the relationship between miR-1236 and BC, Yu et al. demonstrated that circ_0102273 and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) protein showed high expression in BC cells and inversely correlated with miR-1236, and confirmed that miR-1236 was sponged by circ_0102273.