IL1B and systemic sclerosis: Increased IL-1β levels have been observed in serum and bronchoalveolar lavage fluid of SSc patients [42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73].