In comparison to the equivalent normal tissues, TIMP3 was significantly reduced in various cancer types, including lung adenocarcinoma (LUAD), kidney chromophobe (KICH), lung squamous cell carcinoma (LUSC), colorectal cancer (CRC), and uterine carcinosarcoma (UCS) tissues (Figure 1B). This evidence concerns the gene TIMP3 and uterine carcinosarcoma.