Furthermore, pan-cancer analyses using TNMplot and survival in the KM plotter and GENT2 tools confirmed YY1 overexpression across multiple cancer types—including colon cancer, esophagus cancer, AML, ovarian cancer, lung adenocarcinoma, and BC—whereas high YY1 expression at transcriptomic level correlates with poor survival in BC patients. The gene discussed is YY1; the disease is colonic neoplasm.