Later, García-Manero et al. expanded the scope by analyzing the methylation status of ten gene promoters in adult ALL, including ABCB1, THBS2, MYOD1, ESR1, CDKN2B, THBS1, MME, ABL1, CDKN2A, and TP73. The gene discussed is CDKN2A; the disease is acute lymphoblastic leukemia.