SPOP and posterior cortical atrophy: Misexpression of other loci with high penetrance have also been associated with PCa, including long non-coding (Inc)RNA RPS-997D16.2, AR, BRCA2, HOXB13, TP53, RB1, PTEN, TMPRSS2-ERG fusion, ETV1, ETV4, FLI1, SPOP, FOXA1, IDH1, BRCA2, ATM, MYC, and BRAF. Although they might have clinical utility, their possible value in predicting cancer risk and treatment options remain under study [19,20,21,22,23,24,25].