Nucleoside diphosphate-linked moiety X-type motif 1 (NUDT1), also known as MTH1, sanitizes oxidized purine nucleotides such as 8-oxo-dGTP to prevent their incorporation into DNA, and as highlighted by Tong et al., plays a significant role in regulating oxidative stress and maintaining mitochondrial function in glioblastoma cells, which could have significant implications for future therapies [108]. This evidence concerns the gene NUDT1 and glioblastoma.