TRPM2 and obesity due to melanocortin 4 receptor deficiency: Among the TRP family, certain members, such as transient receptor potential canonical 1 (TRPC1) [11,12], transient receptor potential canonical 6 (TRPC6) [13], and transient receptor potential melastatin 2 (TRPM2) [14], have been implicated in obesity, oxidative stress, and kidney diseases [15,16].