INS and atherosclerosis: From KEGG enrichment analysis of glycolipid metabolism-related pathways, the “Lipid and atherosclerosis”, “Non-alcoholic fatty liver disease”, “Alcoholic liver disease”, “FoxO signaling pathway”, “Insulin resistance”, “HIF-1 signaling pathway”, “Mitophagy”, “Sphingolipid signaling pathway”, “AMPK signaling pathway”, “Steroid hormone biosynthesis”, and “Linoleic acid metabolism” emerged as significantly enriched (Figure 6C).