HAVCR1 and Hyperoxaluria: In rats fed with an HP diet, we showed a successful induction of hyperoxaluria (Figure 1A), which is associated with increases in the urinary levels of KIM-1 (Figure 1B); the degree of urine supersaturation as an ion activity product of CaOx [AP(CaOx)] index (Figure 1C) increased in a time-dependent manner from 3 to 28 days.