In a recent study, B. intestinihominis bacteria were found to ameliorate hypertension and hepatic metabolic disorders, and B. intestinihominis-derived acetate enhanced fibroblast growth factor 21 by increasing H3 K27 acetylation of the fibroblast growth factor 21 promoter through inhibition of histone deacetylase 9. This evidence concerns the gene FGF21 and Hypertension.