PPARA and cyclic hematopoiesis: The aim of this study was thus to investigate the exact role of PPARα in hypertrophic phenotype in an in vitro model of CH by using the H9c2 cardiomyoblasts derived from rat ventricles, which represent a well-characterized reliable model for cardiovascular research [9], by the stable silencing of PPARA gene expression by the short hairpin RNA (shRNA) approach.