Utilizing cervical scrapings as a potential genetic material, coupled with the use of DNA hypermethylation in specific genes, including CDO1, CELF4, BHLHE22, POU4F3, MAGI2, CADM1, MAL, miR124-2, ZSCAN12, and GYPC, has been investigated for endometrial cancer detection [13,16,21,24]. Here, BHLHE22 is linked to endometrial cancer.