Levels of IL-1β, IL-4, IL-6, CXCL5, CXCL12, CXCL14, MIF, IGF-1, TGFβ-1, and CCL21 were increased in one or more sarcoma cohorts compared with controls, and levels of IL-15 and IL-16 were significantly lower in one or more sarcoma cohorts compared to healthy controls (Figure 4 and Supplementary Table S2). This evidence concerns the gene IL6 and sarcoma.