In Ewing sarcoma, there were 21 significant relationships, including IL-4/IL-1β (r2 = 0.55, p = 0.00048), IL-4/IL-8 (r2 = 0.68, p = 0.0000047), CXCL14/IL-15 (r2 = 0.61, p = 0.00013), and CXCL5/CXCL12 (r2 = 0.64, p = 0.000030). The gene discussed is CXCL8; the disease is Ewing sarcoma.