More recently, stanniocalcin-1 (STC-1), a microRNA-regulated secreted glycoprotein with physiological functions in autocrine-paracrine signalling, has been recognised as a metastasis-promoting factor in various cancers, including glioblastoma, by activating PI3K/AKT and JNK signalling pathways [57]. The gene discussed is STC1; the disease is glioblastoma.