Our findings revealed significant immunopositivity for Cytokeratin 8/18 (CK8/18) and Cytokeratin 19 (CK19) in NK-NPC cases compared to benign controls (p < 0.001), supporting our hypothesis based on data from squamous cell carcinomas at other anatomical sites [15]. The gene discussed is KRT8; the disease is nasopharyngeal carcinoma.