NLRP3 and post-traumatic stress disorder: Grzesińska and Ogłodek [82] described the interaction between NLRP3, matrix metalloproteinases (MMP-2, MMP-9), and GABAergic signaling in PTSD, suggesting that inflammasome-driven extracellular matrix remodeling and impaired inhibitory neurotransmission may synergistically worsen neuroinflammation and cognitive–emotional dysfunction.