An American multicenter study [24] also evaluated the methylation of six previously identified PCa-related DMGs (pyrosequencing; PCa n = 52, normal tissues n = 77), confirming the hypermethylation of CAV1, EVX1, PLAG2G16, and SPAG4 and hypomethylation of FGF1 and NCR2 in PCa relative to control tissues. This evidence concerns the gene FGF1 and posterior cortical atrophy.