In PCa, the sensitivity and specificity for cancer detection were 100% and 91.7% for EMX1, 78.6% and 91.7% for Chr5q14.1, 57.1%, and 91.7% for NXPH1, and reached 100% and 87.5% for the combined triplex methylation score. The gene discussed is EMX1; the disease is posterior cortical atrophy.