NPPB and systemic sclerosis: Mean sCysC (1.12 ± 0.34 mg/L vs. 0.66 ± 0.23 mg/L, p < 0.001), suPAR (4.86 ± 1.69 ng/mL vs. 2.20 ± 0.43 ng/mL, p < 0.001), NT-proBNP (7.09 ± 13 pg/mL vs. 0.42 ± 0.16 pg/mL, p < 0.001), troponin (3.77 ± 3.41 ng/L vs. 1.92 ± 1.34 ng/L, p < 0.001), galectin-3 (6327.08 ± 2393.43 pg/mL vs. 2264.08 ± 535.51 pg/mL, p < 0.001) and urinary protein levels (7.03 ± 1.97 mg/dL vs. 5.51 ± 0.43 mg/dL, p < 0.001) were significantly higher in SSc patients compared to HC.