Ifit3, as a key member of the interferon-inducible protein family, exhibits vital roles in innate antiviral immunity and changes in cellular biology [46], including cell proliferation, apoptosis, and differentiation, as well as exacerbating inflammation-mediated tumor growth via interferon signaling, RIG-I-like receptors, and the NF-κB pathway [47]. The gene discussed is NFKB1; the disease is neoplasm.